Gamma Secretase

I’m still really upset from yesterday. I wonder if Dad’s forgetting the cruise means that his brain can no longer make new memories?

I’m thinking about enrolling him in a clinical trial of a gamma secretase inhibitor. Gamma secretase is involved in the formation of the plaques that take over the brains of people with Alzheimer’s (that was the simple version), and they are testing a new drug. It’s a placebo trial, so he might not get the drug at first, but all patients in the trial will eventually be switched to the drug, so even if he’s in the placebo group at first, he’ll get the drug sooner than if we wait for it to go through the whole testing and approval process. It may not work, but none of the currently approved drugs for Alzheimer’s do any good.

I’m going to start by calling to get the information and take it from there.